Will these covers work with the factory door latch mechanism?

Yes. These are overlay covers that sit on top of your existing handles; the latch and lock function remains unchanged. Your door operation stays completely normal.

Do I need to remove anything from the door to install these?

You'll need to remove the factory door handle covers to access the mounting points. The install process is straightforward with basic hand tools — plan 15–20 minutes per side.

Should I paint these before installing, or use them as-is?

They ship primed and ready to install in flat black. You can bolt them on immediately or sand and paint them to match custom colors or finishes before mounting.