Harrison Ford stars as eminent Chicago surgeon Dr Richard Kimble in this hugely successful thriller based on the 1960s American television series. Married to wealthy heiress Helen (Sela Ward), he arrives home one night to find his wife murdered and a one-armed man in his house. Due to incriminating evidence and prime motivation, Kimble is wrongly convicted for murder.

However, on his way to death row he is involved in a spectacular train crash that precipitates his escape. Kimble then strives to prove his innocence, whilst staying one step ahead of the dogged US Marshal Sam Gerard (an Oscar-winning Tommy Lee Jones).